pentobarbital will reduce the level or outcome of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.
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pentobarbital will reduce the extent or outcome of tolterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lower the level or result of ethotoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.
pentobarbital will minimize the extent or effect of etonogestrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the level or influence of ripretinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Dosage ought to be reduced from the elderly or debilitated due to the fact these sufferers could be additional delicate to barbiturates. Dosage must be reduced for patients with impaired renal functionality or hepatic disease.
Phenobarbital lowers the plasma amounts of dicumarol (identify Earlier applied: bishydroxycoumarin) and leads to a lessen in anticoagulant activity as measured because of the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing elevated metabolism and reduced anticoagulant response of oral anticoagulants (e.
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pentobarbital will decrease the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will decrease the level or result of duvelisib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration with a strong CYP3A inducer decreases duvelisib area under the curve (AUC), which may reduce duvelisib efficacy.
pentobarbital will reduce the extent or outcome of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or result of parecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.
In Severe overdose, all electrical action inside the brain could cease, through which scenario a “flat” EEG Typically equated with clinical death can't be acknowledged.